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1992 1
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The following term was not found in PubMed: 279 12580
Page 1
Phosphodiesterase-5 Gln817 is critical for cGMP, vardenafil, or sildenafil affinity: its orientation impacts cGMP but not cAMP affinity.
Zoraghi R, Corbin JD, Francis SH. Zoraghi R, et al. J Biol Chem. 2006 Mar 3;281(9):5553-8. doi: 10.1074/jbc.M510372200. Epub 2006 Jan 5. J Biol Chem. 2006. PMID: 16407275 Free article.
In cGMP-specific PDE5, Gln(775) constrains the orientation of the invariant Gln(817) side chain, which forms bidentate bonds with 5'-GMP, vardenafil, sildenafil, and 3-isobutyl-1-methylxanthine (IBMX) (Sung, B. J., Hwang, K. Y., Jeon, Y. H., Lee, J. I., Heo, Y. S., Kim, J. …
In cGMP-specific PDE5, Gln(775) constrains the orientation of the invariant Gln(817) side chain, which forms bidentate bonds with 5'-GMP, va …
The unfolded protein response is necessary but not sufficient to compensate for defects in disulfide isomerization.
Kim JH, Zhao Y, Pan X, He X, Gilbert HF. Kim JH, et al. J Biol Chem. 2009 Apr 17;284(16):10400-8. doi: 10.1074/jbc.M900377200. Epub 2009 Feb 20. J Biol Chem. 2009. PMID: 19233841 Free PMC article.
., Winther, J. R., Holmgren, A., Lundstrom-Ljung, J., and Gilbert, H. F. (2004) J. Biol. Chem. 279, 49780-49786). We show here that there are multiple ways to compensate for defects in disulfide formation and isomerization in the ER. ...
., Winther, J. R., Holmgren, A., Lundstrom-Ljung, J., and Gilbert, H. F. (2004) J. Biol. Chem. 279, 49780-49786). We show here that t …
Salicylihalamide A inhibits the V0 sector of the V-ATPase through a mechanism distinct from bafilomycin A1.
Xie XS, Padron D, Liao X, Wang J, Roth MG, De Brabander JK. Xie XS, et al. J Biol Chem. 2004 May 7;279(19):19755-63. doi: 10.1074/jbc.M313796200. Epub 2004 Mar 3. J Biol Chem. 2004. PMID: 14998996 Free article.
The newly identified specific V-ATPase inhibitor, salicylihalamide A, is distinct from any previously identified V-ATPase inhibitors in that it inhibits only mammalian V-ATPases, but not those from yeast or other fungi (Boyd, M. R., Farina, C., Belfiore, P., Gagliardi, S., Kim …
The newly identified specific V-ATPase inhibitor, salicylihalamide A, is distinct from any previously identified V-ATPase inhibitors in that …
FAF1 suppresses IkappaB kinase (IKK) activation by disrupting the IKK complex assembly.
Park MY, Moon JH, Lee KS, Choi HI, Chung J, Hong HJ, Kim E. Park MY, et al. J Biol Chem. 2007 Sep 21;282(38):27572-7. doi: 10.1074/jbc.C700106200. Epub 2007 Aug 7. J Biol Chem. 2007. PMID: 17684021 Free article.
Taken together, FAF1 robustly suppresses NF-kappaB activation through the inhibition of IKK activation in combination with previously reported cytoplasmic retention of NF-kappaB p65 (Park, M. Y., Jang, H. D., Lee, S. Y., Lee, K. J., and Kim, E. (2004) J. Biol. Chem. …
Taken together, FAF1 robustly suppresses NF-kappaB activation through the inhibition of IKK activation in combination with previously report …
Calmodulin is involved in the Ca2+-dependent activation of ceramide kinase as a calcium sensor.
Mitsutake S, Igarashi Y. Mitsutake S, et al. J Biol Chem. 2005 Dec 9;280(49):40436-41. doi: 10.1074/jbc.M501962200. Epub 2005 Oct 3. J Biol Chem. 2005. PMID: 16203736 Free article.
We recently demonstrated that the activation of ceramide kinase (CERK) and the formation of its product, ceramide 1-phosphate (C1P), are necessary for the degranulation pathway in mast cells and that the kinase activity of this enzyme is completely dependent on the intracellular …
We recently demonstrated that the activation of ceramide kinase (CERK) and the formation of its product, ceramide 1-phosphate (C1P), are nec …
Proproliferative functions of Drosophila small mitochondrial heat shock protein 22 in human cells.
Wadhwa R, Ryu J, Gao R, Choi IK, Morrow G, Kaur K, Kim I, Kaul SC, Yun CO, Tanguay RM. Wadhwa R, et al. J Biol Chem. 2010 Feb 5;285(6):3833-3839. doi: 10.1074/jbc.M109.080424. Epub 2009 Nov 30. J Biol Chem. 2010. PMID: 19948727 Free PMC article.
Its overexpression results in an extension of life span (>30%) (Morrow, G., Samson, M., Michaud, S., and Tanguay, R. M. (2004) FASEB J. 18, 598-599 and Morrow, G., Battistini, S., Zhang, P., and Tanguay, R. M. (2004) J. Biol. Chem. 279, 43382-43385). Long lived f …
Its overexpression results in an extension of life span (>30%) (Morrow, G., Samson, M., Michaud, S., and Tanguay, R. M. (2004) FAS …
Hepatitis B virus X protein induces expression of Fas ligand gene through enhancing transcriptional activity of early growth response factor.
Yoo YG, Lee MO. Yoo YG, et al. J Biol Chem. 2004 Aug 27;279(35):36242-9. doi: 10.1074/jbc.M401290200. Epub 2004 Jun 1. J Biol Chem. 2004. PMID: 15173177 Free article.
Since the Fas/FasL signaling pathway requires transcriptional induction of the FasL gene, elucidation of the precise mechanisms underlying regulation of FasL gene expression may provide useful molecular insights on tumor progression. We and others (Shin, E. C., Shin, J. S., Park, …
Since the Fas/FasL signaling pathway requires transcriptional induction of the FasL gene, elucidation of the precise mechanisms underlying r …
Collagen alpha1(I) gene (COL1A1) is repressed by RFX family.
Sengupta P, Xu Y, Wang L, Widom R, Smith BD. Sengupta P, et al. J Biol Chem. 2005 Jun 3;280(22):21004-14. doi: 10.1074/jbc.M413191200. Epub 2005 Mar 23. J Biol Chem. 2005. PMID: 15788405 Free PMC article.
D. (1999) J. Biol. Chem. 274, 36649-36655; Sengupta, S., Smith, E. M., Kim, K., Murnane, M. J., and Smith, B. D. (2003) Cancer Res. 63, 1789-1797). In normal cells, RFX5 complex along with major histocompatibility class II transactivator (CIITA) is induced by interferon-ga …
D. (1999) J. Biol. Chem. 274, 36649-36655; Sengupta, S., Smith, E. M., Kim, K., Murnane, M. J., and Smith, B. D. (2003) Cancer Res. 6 …
Modulation of Thr phosphorylation of integrin beta1 during muscle differentiation.
Kim SM, Kwon MS, Park CS, Choi KR, Chun JS, Ahn J, Song WK. Kim SM, et al. J Biol Chem. 2004 Feb 20;279(8):7082-90. doi: 10.1074/jbc.M311581200. Epub 2003 Dec 2. J Biol Chem. 2004. PMID: 14660602 Free article.
By using transient elevations of cytosolic free calcium levels triggered by integrin antibody or laminin (Kwon, M. S., Park, C. S., Choi, K., Park, C.-S., Ahnn, J., Kim, J. I., Eom, S. H., Kaufman, S. J., and Song, W. K. (2000) Mol. ...
By using transient elevations of cytosolic free calcium levels triggered by integrin antibody or laminin (Kwon, M. S., Park, C. S., Choi, K. …
Acute alcohol tolerance is intrinsic to the BKCa protein, but is modulated by the lipid environment.
Yuan C, O'Connell RJ, Wilson A, Pietrzykowski AZ, Treistman SN. Yuan C, et al. J Biol Chem. 2008 Feb 22;283(8):5090-8. doi: 10.1074/jbc.M708214200. Epub 2007 Dec 15. J Biol Chem. 2008. PMID: 18084004 Free PMC article.
The BKCa channel plays a central role in the behavioral response to ethanol in Caenorhabditis elegans (Davies, A. G., Pierce-Shimomura, J. T., Kim, H., VanHoven, M. K., Thiele, T. R., Bonci, A., Bargmann, C. ...E., Puig, S. I., Knott, T. K., Lemos, J. R., and Treistman, S. …
The BKCa channel plays a central role in the behavioral response to ethanol in Caenorhabditis elegans (Davies, A. G., Pierce-Shimomura, J. T …
236 results